Hydrochloric Acid → HCID 14098151, compound

HRID 569296Notes

Reaction equation

HRID 569296 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[O:9][CH3:10].[Cl:11][CH2:12][CH2:13][CH2:14][C:15](Cl)=[O:16].[Cl-].[Al+3].[Cl-].[Cl-].Cl>C(Cl)Cl>[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([C:15](=[O:16])[CH2:14][CH2:13][CH2:12][Cl:11])[CH:5]=[CH:4][C:3]=1[O:9][CH3:10]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 161262,3-DichloroanisoleHCID 783704-Chlorobutyryl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 14098151HCID 14098151, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2,3-Dichloroanisole (120 gm, 0.65 mole) and 4-chlorobutyryl chloride (100 gm, 0.709 mole) were dissolved in methylene chloride (425 ml) and aluminum chloride (98.8 g, 0.741) added portionwise with stirring over 30 minutes. The temperature rose to 32° C. and hydrogen chloride was evolved. After stirring for 3 hours, the mixture was poured into ice containing concentrated hydrochloric acid (80 ml). The layers were separated and the aqueous layer extracted with methylene chloride.

Workup

  1. customrose to 32° C.
  2. stirringAfter stirring for 3 hours
  3. customThe layers were separated
  4. extractionthe aqueous layer extracted with methylene chloride

Sources & evidence

ORD record
ord-97a00179896141b4b6440044df366b66
Source dataset
uspto-grants-1988_03
Patent number
US04731471

Reaction notes

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