反应详情

温度

70 °C

Under an argon atmosphere, 2,4-dihydroxybenzaldehyde (3.00 g, 21.7 mmol), potassium carbonate (30.0 g, 217 mmol) and 1-bromodocosane (17.3 g, 44.5 mmol) were added to dehydrating N,N-dimethylformamide (150 mL), and the mixture was stirred at 70° C. overnight. After completion of the reaction, the reaction mixture was poured into purified water (1 L), the mixture was stirred for 1 hr, and the precipitated solid was collected by filtration. The obtained solid was slurry-washed in methanol and filtered, and the obtained solid was dried under reduced pressure to give the title compound (16.3 g, 99.3%) as a white solid.

1. customAfter completion of the reaction
2. additionthe reaction mixture was poured
3. custominto purified water (1 L)
4. stirringthe mixture was stirred for 1 hr
5. filtrationthe precipitated solid was collected by filtration
6. washThe obtained solid was slurry-washed in methanol
7. filtrationfiltered
8. customthe obtained solid was dried under reduced pressure