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HRID575135

反应详情

EQUATION

反应方程式

HRID 575135 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1nc2n(c1C=O)C1CC(C1)c1cc(F)c(Br)cc1-2
HCID86693159

未命名化合物

PRODUCTS

生成物

1
结构：O=Cc1c(C(=O)O)nc2n1C1CC(C1)c1cc(F)c(Br)cc1-2
HCID86693160

未命名化合物

收率 74.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.O
溶剂HCID22242641

Methanol--water (1/1)

CH6O2

PROCEDURE

实验过程

Methyl 9-bromo-10-fluoro-3-formyl-2,5-diazatetracyclo[11.1.1.0[2,6].0[7,12]]pentadeca-3,5,7(12),8,10-pentaene-4-carboxylate (125 mg) was saponified with LiOH in H2O/MeOH to give 90 mg of 9-bromo-10-fluoro-3-formyl-2,5-diazatetracyclo[11.1.1.0[2,6].0[7,12]]pentadeca-3,5,7(12),8,10-pentaene-4-carboxylic acid.