反应详情

Analogously to the preparation of Example 38A, 160 mg (0.15 mmol) of tert-butyl 3-[(5-acetyl-4-amino-1,3-thiazol-2-yl)amino]piperidine-1-carboxylate (Example 49A) and 20 ml of hydrochloric acid in dioxane (4M) gave 40 mg (87% of theory) of the product as a solid.