HCID 67232953, compound → HCID 67233737, compound

HRID 578064Notes

Reaction equation

HRID 578064 reaction equation
[NH2:1][C:2]1[C:17]([N+:18]([O-])=O)=[CH:16][C:5]([C:6]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:7])=[C:4]([F:21])[CH:3]=1>[Pt].C1COCC1.CO>[NH2:1][C:2]1[C:17]([NH2:18])=[CH:16][C:5]([C:6]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:7])=[C:4]([F:21])[CH:3]=1

Participants

5

Reactant 1

HCID 67232953HCID 67232953, compound

Product 1

HCID 67233737HCID 67233737, compound

Reagents, catalysts & solvents 3

HCID 23939PlatinumCatalystHCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 659c from benzyl 4-amino-2-fluoro-5-nitro-benzoate by hydrogenation using platinum on charcoal in THF and methanol.

Sources & evidence

ORD record
ord-3cfe926639c14213acb00bf1ac96df7e
Source dataset
uspto-grants-2015_05
Patent number
US09040565B2

Reaction notes

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