Potassium Carbonate → 4-(2,6-Diethyl-4-methylphenyl)-2,6-dimethyl-5-methylsulfonyl-2,3-dihydro-3-pyridazinone

HRID 579232Notes

Reaction equation

HRID 579232 reaction equation
[CH2:1]([C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:4]=1[C:12](=O)[C:13]([N:15]([CH3:24])[N:16]=[C:17]([CH3:23])[CH2:18][S:19]([CH3:22])(=[O:21])=[O:20])=[O:14])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO>[CH2:1]([C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:4]=1[C:12]1[C:13](=[O:14])[N:15]([CH3:24])[N:16]=[C:17]([CH3:23])[C:18]=1[S:19]([CH3:22])(=[O:21])=[O:20])[CH3:2]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 764689601-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylsulfonyl-2-propylidene)hydrazine

Product 1

HCID 569427174-(2,6-Diethyl-4-methylphenyl)-2,6-dimethyl-5-methylsulfonyl-2,3-dihydro-3-pyridazinone

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a test tube (outside diameter: 21 mm Φ×overall length: 160 mm), 1-[2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylsulfonyl-2-propylidene)hydrazine ((4-34-(1)-39) (201.0 mg), potassium carbonate (115.1 mg), and methanol (757 μl) were added under ice-cooling.

Workup

  1. temperaturecooling

Sources & evidence

ORD record
ord-f4672f69d9bc4df78a4a538b501bb81c
Source dataset
uspto-grants-2015_05
Patent number
US09040709B2

Reaction notes

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