Hydroxylamine → 3-Nitrobenzaldoxime

HRID 580085Notes

Reaction equation

HRID 580085 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)([O-:3])=[O:2].[NH2:12][OH:13]>O>[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=[N:12][OH:13])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 74493-Nitrobenzaldehyde

Product 1

HCID 2191323-NitrobenzaldoximeYield 98%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 5 l of water warmed at 50° C. was 453 g (3 mol) of m-nitrobenzaldehyde added and then, 218 g (3.3 mol) of a 50% aqueous solution of hydroxylamine (manufactured by Nisshin Kako) was added dropwise under stirring and further, stirred at the same temperature for 3 hours. Thereafter the mixture was cooled to room temperature, filtered, washed with water and dried. 488 g of m-nitrobenzaldoxime was obtained. Yield 98%; M.P. 118°-121° C.

Workup

  1. additionadded
  2. stirringfurther, stirred at the same temperature for 3 hours
  3. filtrationfiltered
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-b12bb2840f86471c836f2bdc1ca15390
Source dataset
uspto-grants-1988_06
Patent number
US04751328

Reaction notes

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