Hydroxylamine → 3-Nitrobenzaldoxime

HRID 580090Notes

Reaction equation

HRID 580090 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)([O-:3])=[O:2].[NH2:12][OH:13]>O>[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=[N:12][OH:13])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 74493-Nitrobenzaldehyde

Product 1

HCID 2191323-NitrobenzaldoximeYield 96.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
70 °C

Procedure

151 g (1 mol) of m-nitrobenzaldehyde was added to 1 l of water warmed at 70° C. and 72.6 g (1.1 mol) of a 50% aqueous solution of hydroxylamine was added dropwise under stirring and further, was stirred at the same temperature for one hour. The resulting mixture was cooled to room temperature and crystals thus deposited were filtered, washed with water and dried. 160.5 g of m-nitrobenzaldoxime was obtained (yield 96.6%; M.P. 118°-121° C.).

Workup

  1. stirringfurther, was stirred at the same temperature for one hour
  2. temperatureThe resulting mixture was cooled to room temperature
  3. filtrationcrystals thus deposited were filtered
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-62b58abf40824a51b95bcef7acb97c06
Source dataset
uspto-grants-1988_06
Patent number
US04751328

Reaction notes

Loading…