1-Nitroprop-1-en-2-amine → HCID 86742245, compound

HRID 580515Notes

Reaction equation

HRID 580515 reaction equation
[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:28])[C:14]([C:25](=O)[CH3:26])=[CH:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([N+:22]([O-:24])=[O:23])[CH:17]=3)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:29][C:30]([CH3:35])=[CH:31][N+:32]([O-:34])=[O:33]>C(O)(C)C>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([C:13]([C:14]3[CH:15]([C:16]4[CH:21]=[CH:20][CH:19]=[C:18]([N+:22]([O-:24])=[O:23])[CH:17]=4)[C:31]([N+:32]([O-:34])=[O:33])=[C:30]([CH3:35])[NH:29][C:25]=3[CH3:26])=[O:28])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 714047121-Nitroprop-1-en-2-amineHCID 86162491HCID 86162491, compound

Product 1

HCID 86742245HCID 86742245, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

2.5 g (10 mmol) of crude 2-acetyl-3-(3-nitrophenyl)-2-propenoic acid 4-phenyl-piperazide and 2.5 g (25 mmol) of 2-amino-1-nitro-1-propene are heated in 15 ml of isopropanol at 60° C. for 6 hours. The crude product which has precipitated out is crystallized from isopropanol.

Workup

  1. customThe crude product which has precipitated out
  2. customis crystallized from isopropanol

Sources & evidence

ORD record
ord-f503b39e6e1d4a8fb286936bffd064ce
Source dataset
uspto-grants-1988_06
Patent number
US04753936

Reaction notes

Loading…