4-(2-Oxopropyl)benzoyl chloride → 1-(4-Carboisopropoxyphenyl)propan-2-one

HRID 580634Notes

Reaction equation

HRID 580634 reaction equation
[CH2:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3]>C(O)(C)C>[C:9]([C:8]1[CH:12]=[CH:13][C:5]([CH2:1][C:2](=[O:3])[CH3:4])=[CH:6][CH:7]=1)([O:3][CH:2]([CH3:4])[CH3:1])=[O:10]

Participants

3

Reactant 1

HCID 201341784-(2-Oxopropyl)benzoyl chloride

Product 1

HCID 201341771-(4-Carboisopropoxyphenyl)propan-2-one

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Isopropanol (30 ml) was added to 4-acetonylbenzoyl chloride (2.61 g) and the solution left at room temperature 3 days. Removal of the solvent gave the title compound as an oil. γ (CDCl3) 8.66 (3H, d, J=7 Hz), 7.88 (3H, s), 6.28 (2H, s), 4.78 (1H, h, J=7 Hz), 2.80 (2H, d, J=9 Hz) 2.04 (2H, d, J=9 Hz).

Workup

  1. customRemoval of the solvent

Sources & evidence

ORD record
ord-2b618e91ac3c4b489d43117c85efbcca
Source dataset
uspto-grants-1988_06
Patent number
US04753962

Reaction notes

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