Acetic Acid → HCID 54561915, compound

HRID 581051Notes

Reaction equation

HRID 581051 reaction equation
[CH2:1]([S:8][C:9]1[S:10][C:11]2[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:12]=2[N:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.OO.[OH2:21].C(O)(=[O:24])C>>[CH2:1]([S:8]([C:9]1[S:10][C:11]2[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:12]=2[N:13]=1)(=[O:24])=[O:21])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 962WaterHCID 14749857HCID 14749857, compound

Product 1

HCID 54561915HCID 54561915, compoundYield 60.6%

Conditions

Temperature
100 °C

Procedure

0.45 g (2 mmol) of 2-benzylmercapto-6-hydroxy-benzothiazole are dissolved in 15 ml of warm glacial acetic acid and at 50° C. 2.5 ml of 35% hydrogen peroxide is added. The mixture is stirred for 1 hour at 50° C. and 20 minutes at 100° C. It is then added to water, neutralised with soda and extracted with ethyl acetate. The extracts are dried and evaporated down. The evaporation residue is digested with a little ether and suction filtered. Yield: 60.6% of theory, Melting point: 188-189° C.

Workup

  1. extractionextracted with ethyl acetate
  2. customThe extracts are dried
  3. customevaporated down
  4. filtrationfiltered

Sources & evidence

ORD record
ord-57f53f01255642af840942f8e4604c04
Source dataset
uspto-grants-1999_07
Patent number
US05919807

Reaction notes

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