反应详情

Trimethylsilylisocyanate (3.2 ml; 85%) was added to a solution of 4-amino-benzylamine (1.55 ml) in dry THF (40 ml). A white solid precipitated. The reaction mixture was stirred at r.t. overnight then the precipitate was filtered and washed with ethyl acetate giving the title compound (1.2 g) as a white solid.

1. customA white solid precipitated
2. filtrationthe precipitate was filtered
3. washwashed with ethyl acetate giving the title compound (1.2 g) as a white solid