反应详情

Linoleic acid (100 g; purity 95%, 356 mmoles) was added dropwise over a period of 0.5 hours to a stirred mixture of oxalyl chloride (42 ml; 481 mmoles) and of hexane (120 ml) under nitrogen. After the addition the mixture was refluxed for 1.5 hours and then evaporated under reduced pressure (60° C.; 0.5 mm Hg) to give 107 grams of linoleoyl chloride as an oil.

1. additionAfter the addition the mixture
2. temperaturewas refluxed for 1.5 hours
3. customevaporated under reduced pressure (60° C.; 0.5 mm Hg)