Hydrochloric Acid → HCID 70347532, compound

HRID 582036Notes

Reaction equation

HRID 582036 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH2:15][CH2:14][C:13](=[O:16])[C:12]=2[C:17]2[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[ClH:23]>C(Cl)Cl>[ClH:23].[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH2:15][CH2:14][C:13](=[O:16])[C:12]=2[C:17]2[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 97968433-(4-methylsulfonylphenyl)-2-pyridin-3-ylcyclopent-2-en-1-one

Product 1

HCID 70347532HCID 70347532, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 3-(4-(methylsulfonyl)phenyl)-2-(3-pyridinyl)-2-cyclopenten-1-one (5.0 g, 15.96 mmol) in CH2Cl2 (50 mL) was passed a stream of HCl gas for 10 min. Excess HCl was removed by bubbling a stream of air through the solution. The solution was then concentrated and swished in Et2O to give 5.7 g of the title compound.

Workup

  1. customfor 10 min
  2. customExcess HCl was removed
  3. customby bubbling a stream of air through the solution
  4. concentrationThe solution was then concentrated

Sources & evidence

ORD record
ord-d177aa9e1096408ea3a6d985ea612dd1
Source dataset
uspto-grants-1999_07
Patent number
US05922742

Reaction notes

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