Potassium Carbonate → HCID 21221840, compound

HRID 582445Notes

Reaction equation

HRID 582445 reaction equation
C1[CH:6]=[C:5](Cl)[CH:4]=[C:3]([C:8]([O:10]O)=O)C=1.[C:12]([O:17]C(CC=C)C)(=[O:16])[C:13]([CH3:15])=[CH2:14].C(=O)([O-])[O-].[K+].[K+]>C(Cl)(Cl)Cl.O>[C:12]([O:17][CH:5]([CH2:4][CH:3]1[O:10][CH2:8]1)[CH3:6])(=[O:16])[C:13]([CH3:15])=[CH2:14]

Participants

6

Reactant 3

HCID 11430Potassium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 10773191HCID 10773191, compound

Product 1

HCID 21221840HCID 21221840, compoundYield 61.5%

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6212ChloroformSolvent

Conditions

Temperature
23 °C

Procedure

A solution of m-CPBA (32 g) in chloroform (150 ml) was cooled in cold water and then 4-penten-2-yl methacrylate (14 g) was added. The mixture was stirred at 23° C. for 6 hours. The post-reaction mixture was then poured into dilute potassium carbonate (300 ml) and the organic layer was separated. The organic layer was washed with three more portions of carbonate, finally with water and then dried. Remaining solvents were then removed and the residue was subjected to chromatography on silica gel. As a result pure 4,5-epoxypent-2-yl methacrylate (9.5 g) was isolated.

Workup

  1. customthe organic layer was separated
  2. washThe organic layer was washed with three more portions of carbonate, finally with water
  3. customdried
  4. customRemaining solvents were then removed

Sources & evidence

ORD record
ord-2179f328a675400eba6a87fbe6f9ea36
Source dataset
uspto-grants-1999_07
Patent number
US05925253

Reaction notes

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