Methanethiol → HCID 15165079, compound

HRID 582458Notes

Reaction equation

HRID 582458 reaction equation
C([O-])([O-])=O.[K+].[K+].Cl[C:8]1[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16].[CH3:18][SH:19]>CN(C=O)C>[CH3:18][S:19][C:8]1[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16]

Participants

5

Reactant 3

HCID 878MethanethiolHCID 69764-Chloro-3-nitrotolueneHCID 11430Potassium Carbonate

Product 1

HCID 15165079HCID 15165079, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

138 g (1 mol) of K2CO3 are added to a solution of 171.6 g (1 mol) of 4-chloro-3-nitrotoluene in 500 ml of DMF. 1 molar equivalent of methyl mercaptan is passed through, and stirring is continued at 50° C. for 3 h. The reaction mixture is poured on a large amount of ice-water and the precipitate is filtered off under suction, washed with water and dried; 146.3 g (80%) of 4-methylthio-3-nitrotoluene of melting point 71-73° C. are obtained.

Workup

  1. filtrationthe precipitate is filtered off under suction
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-e55d773985f84bdf9ba455d2395154c8
Source dataset
uspto-grants-1999_07
Patent number
US05925596

Reaction notes

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