Ether hydrochloride → HCID 85707177, compound

HRID 582955Notes

Reaction equation

HRID 582955 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Te:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:3].[ClH:18].CCOCC>CCOCC.C(O)(C)C>[ClH:18].[CH3:1][N:2]([CH3:3])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Te:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 2

HCID 10953452Ether hydrochlorideHCID 11809921Benzenemethanamine, N,N-dimethyl-2-(phenyltelluro)-

Product 1

HCID 85707177HCID 85707177, compoundYield 100.3%

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 3776IsopropanolSolvent

Procedure

To a slurry of 2-(N,N-dimethylaminomethyl)-1-phenyltellurobenzene (1.02 g, 3.0 mmol) in ether (50 mL) in a water bath was added dropwise by syringe a hydrogen chloride/ether solution (3.15 mL, 1.0 M, 3.15 mmol). The thick slurry was diluted with isopropanol (20 mL) then filtered. The white solid was washed with ether, and air dried, to give the product (1.13 g, 95%). 1H NMR (CDCl3) d 2.6 (1H, br s), 8.13 (1H, d, J=7.5), 7.80 (1H, d, J=7.7), 7.52-7.48 (3H, m), 7.26-7.17 (4H, m), 4.44 (2H, d, J=5.8), 2.68 (6H, d, J=4.5). Anal. calc'd for C15H18ClNTe: C, 48.00; H, 4.83; N, 3.73. Found: C, 47.97; H, 4.87; N, 3.65.

Workup

  1. filtrationthen filtered
  2. washThe white solid was washed with ether, and air
  3. customdried

Sources & evidence

ORD record
ord-50e02106c9ac492eaec25a4b3c741098
Source dataset
uspto-grants-1999_07
Patent number
US05928886

Reaction notes

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