Sulfur → HCID 70109822, compound

HRID 583715Notes

Reaction equation

HRID 583715 reaction equation
[CH3:1][O:2][C:3](=[O:25])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[NH2:24])=S)=[CH:6][CH:5]=1.[S]>CCO>[CH3:1][O:2][C:3](=[O:25])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]2[NH:24][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=3[N:17]=2)=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 5362487SulfurHCID 54346156HCID 54346156, compound

Product 1

HCID 70109822HCID 70109822, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 36-4 (2.5 g, 7.0 mmol), HgO (3.0 g, 13.9 mmol), sulfur (42 mg) and EtOH (50 mL) was refluxed for 2.5 h. Filtration and concentration gave a brown gum which was purified by flash chromatography (silica, 9:1 CH2Cl2 /CH3OH) to provide 36-5 as a tan solid.

Workup

  1. temperaturewas refluxed for 2.5 h
  2. filtrationFiltration and concentration
  3. customgave a brown gum which
  4. customwas purified by flash chromatography (silica, 9:1 CH2Cl2 /CH3OH)

Sources & evidence

ORD record
ord-668f76c9095b4c29bff14c25cef7872f
Source dataset
uspto-grants-1999_07
Patent number
US05929120

Reaction notes

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