Benzylamine → HCID 69693809, compound

HRID 583792Notes

Reaction equation

HRID 583792 reaction equation
[CH3:1][O:2][C:3]1[CH:7]=[C:6]([C:8]([OH:10])=[O:9])[S:5][C:4]=1[C:11]([OH:13])=O.[CH2:14]([NH2:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>CN(C=O)C>[CH2:14]([N:21]([CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:11]([C:4]1[S:5][C:6]([C:8]([OH:10])=[O:9])=[CH:7][C:3]=1[O:2][CH3:1])=[O:13])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 22342518HCID 22342518, compound

Product 1

HCID 69693809HCID 69693809, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
60 °C

Procedure

A mixture of 3-methoxy-thiophene-2,5-dicarboxylic acid (0.382 g), benzylamine (0.41 mL), N,N′-carboxyl≈diimidazole (0.66 g), and DMF was heated at 60° C. to yield 0.39 g of 3-methoxy-thiophene-2,5-dicarboxylic acid bis benzylamide; MI-APCI+ 381.1; Elem. Anal. (C21H20N2O3S); Calc'd: C, 66.30; H, 5.30; N, 7.36. Found: C, 66.52; H, 5.06; N, 7.41.

Sources & evidence

ORD record
ord-2524547aeeba4a1cb901c8497647047d
Source dataset
uspto-grants-2005_08
Patent number
US06924276B2

Reaction notes

Loading…