Ethanol → 3-Nitrobenzaldoxime

HRID 586403Notes

Reaction equation

HRID 586403 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)([O-:3])=[O:2].C(O)C.Cl.[NH2:16][OH:17]>O>[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=[N:16][OH:17])([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 702EthanolHCID 74493-NitrobenzaldehydeHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 2191323-Nitrobenzaldoxime

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of 3-nitrobenzaldehyde (5.0 g; 33.1 mmol) in abs. ethanol (40 ml) was added hydroxylamine, hydrochloride (3.45 g; 49.6 mmol) and the resulting suspension was heated to reflux overnight. The cooled mixture was poured into water (100 ml) and the product was filtered off and dried. Yield: 4.5 g (82%).

Workup

  1. temperaturethe resulting suspension was heated
  2. temperatureto reflux overnight
  3. filtrationthe product was filtered off
  4. customdried

Sources & evidence

ORD record
ord-defe8fc6f1284b198d8910d999b060dd
Source dataset
uspto-grants-2005_08
Patent number
US06936613B2

Reaction notes

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