Thioglycolic Acid → HCID 131725106, compound

HRID 586757Notes

Reaction equation

HRID 586757 reaction equation
[OH-].[Li+:2].[SH:3][CH2:4][C:5]([OH:7])=[O:6]>CC(O)C>[OH2:6].[Li+:2].[Li+:2].[SH:3][CH2:4][C:5]([O-:7])=[O:6].[SH:3][CH2:4][C:5]([O-:7])=[O:6]

Participants

4

Reactant 2

HCID 1133Thioglycolic AcidHCID 3939Lithium Hydroxide

Product 1

HCID 131725106HCID 131725106, compoundYield 166.2%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Finely crushed lithium hydroxide (1.03 g, 43 mmol) was added to a solution of mercaptoacetic acid (1.5 mL, 1.97 g, 21.5 mmol) in 2-propanol (20 mL). The mixture was stirred for 1.5 hours at room temperature. All solvent was removed by rotary evaporation. This gave a fine white powder (2.55 g, 97%). The mass recovery and NMR suggest that the salt forms as a monohydrate.

Workup

  1. customAll solvent was removed by rotary evaporation

Sources & evidence

ORD record
ord-886ee9bf327747ce8f41a7bee05e51a3
Source dataset
uspto-grants-2005_08
Patent number
US06936712B1

Reaction notes

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