Tert-Butylamine → N-t-Butyl-5-fluoro-2-pyridinecarboxamide

HRID 586803Notes

Reaction equation

[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([OH:10])=O)=[N:6][CH:7]=1.[C:11]([NH2:15])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([NH:15][C:8]([C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][N:6]=1)=[O:10])([CH3:14])([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 27628765-fluoropyridine-2-carboxylic Acid

Product 1

HCID 22336253N-t-Butyl-5-fluoro-2-pyridinecarboxamide

Procedure

The title compound was prepared by the same method as that described in Example 39-3), using 5-fluoro-2-pyridinecarboxylic acid and t-butylamine.

Sources & evidence

ORD record: ord-2711899726134f7d9761207e9fb0eeca
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06936736B2

Reaction notes

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