反应详情

D7 (1 g, 3.409 mmol) and triethylorthoformate (7.577 g, 51.13 mmol) in xylene (25 ml) were heated in a sealed tube at 180° C. for 1 h. After cooling, the resulting mixture was concentrated in vacuo. The residue thus obtained was triturated with Et2O to yield compound D8 (0.932 g, 90%).

1. temperatureAfter cooling
2. concentrationthe resulting mixture was concentrated in vacuo
3. customThe residue thus obtained
4. customwas triturated with Et2O