反应详情

温度

80 °C

The solution of 2-chloro-4-methoxy-1-vinylbenzene (290 mg, 1.72 mmol) in dry THF (4 mL) was degassed, and then TMS-CF3 and NaI were added. The mixture was stirred at 80° C. overnight. TLC (100% Hexane) showed the reaction as complete. The mixture was diluted with hexane (20 mL). The inorganic salt was removed by filtration. The filtrate was concentrate in vacuo. The residue was purified via Isolera One (Hexane=100%).

1. customthe reaction as complete
2. customThe inorganic salt was removed by filtration
3. concentrationThe filtrate was concentrate in vacuo
4. customThe residue was purified via Isolera One (Hexane=100%)