反应详情

温度

70 °C

A mixture of 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (1.3 g, 6.3 mmol), N-chlorosuccinimide (0.93 g, 7.0 mmol) and THF (6.6 mL) was stirred at 70° C. for 3 h. The mixture was extracted with EtOAc, dried and concentrated under reduced pressure. The sub-title compound was purified by chromatography on silica gel using 40% EtOAc in hexanes gave the desired compound, 1.456 g, 95%.

1. extractionThe mixture was extracted with EtOAc
2. customdried
3. concentrationconcentrated under reduced pressure
4. customThe sub-title compound was purified by chromatography on silica gel using 40% EtOAc in hexanes