Benzaldehyde → 2-(Benzylideneamino)phenol

HRID 58932Notes

Reaction equation

HRID 58932 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(O)C>[CH:9](=[N:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 58012-Aminophenol

Product 1

HCID 2198092-(Benzylideneamino)phenol

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 2-aminophenol (28.55 g, 261.61 mmol) in ethanol (40 mL), was added benzaldehyde (30 mL, 31.32 g, 295.14 mmol), and this reaction mixture was refluxed for two hours, and left stirring at room temperature overnight. The creamy white precipitate was filtered, washed with ethanol and dried in vacuum oven at 80° C. for 4 hours. Giving 40.27 g (78% yields).

Workup

  1. temperaturethis reaction mixture was refluxed for two hours
  2. waitleft
  3. filtrationThe creamy white precipitate was filtered
  4. washwashed with ethanol
  5. customdried in vacuum oven at 80° C. for 4 hours
  6. customGiving
  7. custom40.27 g (78% yields)

Sources & evidence

ORD record
ord-53a7089bdb5f4d60a3967d01e364c849
Source dataset
uspto-grants-2016_09
Patent number
US09437828B2

Reaction notes

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