反应详情

Ethyl 2-[1-(4-nitrobenzyl)-1H-indazol-3-yl]acetate (340 mg, 1.04 mmol) was dissolved in methanol (20 mL). 10% Pd/C(20 mg) was added, and reacted under hydrogen atmosphere for half an hour. TLC (petroleum ether:ethyl acetate=2:1) indicated that starting material disappeared. It was filtered to remove solid, rotate evaporated to dryness to remove the solvent. The resulting solid was used for the next step directly.

1. customreacted under hydrogen atmosphere for half an hour
2. filtrationIt was filtered
3. customto remove solid
4. customrotate evaporated to dryness
5. customto remove the solvent