反应详情

温度

70 °C

A flask equipped with a stirrer, reflux condenser, dropping funnel and thermometer was charged with 160.3 g (0.8 mol) of 1-t-butyldimethylsilylpiperazine (Synthesis Example 1) and heated at 70° C. Once the internal temperature became steady, 75.8 g (0.88 mol) of methyl acrylate was added dropwise over 2 hours. Stirring was continued for 4 hours at the temperature. On distillation of the reaction solution, 219.9 g of a fraction having a boiling point of 135-137° C./0.4 kPa was collected.

1. customA flask equipped with a stirrer
2. temperaturereflux condenser
3. distillationOn distillation of the reaction solution, 219.9 g of a fraction
4. customwas collected