Methyl Acrylate → HCID 131734485, compound

HRID 590536Notes

Reaction equation

HRID 590536 reaction equation
[CH:1]([Si:4]([CH:14]([CH3:16])[CH3:15])([CH:11]([CH3:13])[CH3:12])[N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1)([CH3:3])[CH3:2].[C:17]([O:21][CH3:22])(=[O:20])[CH:18]=[CH2:19]>>[CH:14]([Si:4]([CH:1]([CH3:3])[CH3:2])([CH:11]([CH3:13])[CH3:12])[N:5]1[CH2:10][CH2:9][N:8]([CH2:19][CH2:18][C:17]([O:21][CH3:22])=[O:20])[CH2:7][CH2:6]1)([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 7294Methyl AcrylateHCID 131734484HCID 131734484, compound

Product 1

HCID 131734485HCID 131734485, compound

Conditions

Temperature
70 °C

Procedure

A flask equipped with a stirrer, reflux condenser, dropping funnel and thermometer was charged with 194.0 g (0.8 mol) of 1-triisopropylsilylpiperazine (Synthesis Example 2) and heated at 70° C. Once the internal temperature became steady, 75.8 g (0.88 mol) of methyl acrylate was added dropwise over 2 hours. Stirring was continued for 4 hours at the temperature. On distillation of the reaction solution, 250.0 g of a fraction having a boiling point of 163-164° C./0.4 kPa was collected.

Workup

  1. customA flask equipped with a stirrer
  2. temperaturereflux condenser
  3. distillationOn distillation of the reaction solution, 250.0 g of a fraction
  4. customwas collected

Sources & evidence

ORD record
ord-d06a457e19fb40948d21e6dbb9019035
Source dataset
uspto-grants-2016_01
Patent number
US09233988B2

Reaction notes

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