2,6-Dichlorobenzamide → 2,6-Dichlorobenzoyl isocyanate

HRID 59260Notes

Reaction equation

HRID 59260 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:13](Cl)=[O:14]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[C:3]=1[C:4]([N:6]=[C:13]=[O:14])=[O:5]

Participants

4

Reactant 2

HCID 161832,6-DichlorobenzamideHCID 65578Oxalyl chloride

Product 1

HCID 129127392,6-Dichlorobenzoyl isocyanateYield 88%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 2,6-dichlorobenzamide (1.00 g, 5.26 mmol), oxalyl chloride (0.795 g, 6.31 mmol) and toluene (10 mL) to afford 1.00 g of desired product.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-5fca01153ddf4ee394514e15cea7298b
Source dataset
uspto-grants-2016_09
Patent number
US09439890B2

Reaction notes

Loading…