2,2,6,6-Tetramethylpiperidine → HCID 178418821, compound

HRID 593732Notes

Reaction equation

HRID 593732 reaction equation
[CH3:1][C:2]1([CH3:10])[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[NH:3]1.C([Li:15])CCC>C1COCC1>[Li:15][N:3]1[C:4]([CH3:9])([CH3:8])[CH2:5][CH2:6][CH2:7][C:2]1([CH3:10])[CH3:1]

Participants

4

Reactant 2

HCID 130352,2,6,6-TetramethylpiperidineHCID 178418339Butyllithium

Product 1

HCID 178418821HCID 178418821, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of LTMP was prepared by reaction of 2,2,6,6-tetramethylpiperidine (0.151 mL, 0.896 mmol) in THF (5.6 mL) and n-butyllithium (0.358 mL, 0.896 mmol) at −30° C. and then at 0° C. for 30 min.

Workup

  1. customat 0° C.
  2. customfor 30 min.

Sources & evidence

ORD record
ord-3535987bb6f24af6b44c5c03a83aba48
Source dataset
uspto-grants-2016_01
Patent number
US09242967B2

Reaction notes

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