反应详情

To methyl 5-methylnicotinate (2 g), PtO2 (100 mg) was added. The reaction flask was put under vacuum, and 125 N HCl in methanol (15 mL) was added. The reaction was put under 40 psi hydrogen gas and shaked overnight. The reaction mixture was filtered through celite and concentrated under vacuo. The crude product was progressed to the next step without further purification.

1. additionwas added
2. filtrationThe reaction mixture was filtered through celite
3. concentrationconcentrated under vacuo
4. customThe crude product was progressed to the next step without further purification