HRID596361

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID61147

Acetyl bromide, 2-bromo-

C2H2Br2O

HCID517045

Sodium Acetate

C2H3NaO2

结构：NNC1=Nc2ccc([N+](=O)[O-])cc2C(c2ccccc2Cl)=NC1

HCID20291856

未命名化合物

PRODUCTS

生成物

结构：O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CBr)n1-2

HCID20291832

未命名化合物

PROCEDURE

实验过程

In the manner given in Preparation 10, 7 -nitro-5(o-chlorophenyl)-3H-1,4-benzodiazepin-2-yl hydrazine is reacted with bromoacetyl bromide and after 1.5 hours with sodium acetate, then refluxed to give 8-nitro-1(bromomethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine. Preparation 15 1-(Chloromethyl)-7-(trifluoromethyl)-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine

WORKUP

后处理

temperaturerefluxed