Sodium Bicarbonate → HCID 21449798, compound

HRID 596425Notes

Reaction equation

HRID 596425 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH2:6]([N+:13]1[C:18](Cl)=[CH:17][C:16]([NH2:20])=[CH:15][N:14]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C(=O)(O)[O-].[Na+]>>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH2:6]([N+:13]1[CH:18]=[CH:17][C:16]([NH2:20])=[CH:15][N:14]=1)[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 516892Sodium BicarbonateHCID 21449825HCID 21449825, compound

Product 1

HCID 21449798HCID 21449798, compoundYield 67.3%

Procedure

The procedure of Example 4 is repeated but 13 parts of 1-benzyl-4-amino-6-chloropyridazinium perchlorate is used and 10 parts of sodium bicarbonate is used instead of triethylamine. 9.6 parts (67.3% of theory) of 1-benzyl-4-aminopyridazinium perchlorate is obtained from the filtrate from the reaction mixture; C11H12O4N3Cl, melting point 127° to 129° C after having been recrystallized from water.

Sources & evidence

ORD record
ord-13e8eda2be054545a7fe12c0c12d18be
Source dataset
uspto-grants-1977_03
Patent number
US04011220

Reaction notes

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