反应详情

(1-Hydroxy-2-benzyl-2methyl-6,7-dichloro-5-indanyloxy)acetic acid is prepared following subtantially the same procedure described in Example 4, Step F, using the following substances: 2-benzyl-2-methyl-6,7-dichloro-1,5indandiol (4.8 g., 0.015 mole); potassium carbonate (3.6 g.); ethyl bromoacetate (3.1 ml.); and dimethylformamide (35 ml.), and hydrolyzing the resultant ester with aqueous sodium hydroxide in accordance with Example 4, Step F, gives (1-hydroxy-2-benzyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid.

1. custom(1-Hydroxy-2-benzyl-2methyl-6,7-dichloro-5-indanyloxy)acetic acid is prepared