Hydrochloric Acid → HCID 178435402, compound

HRID 597015Notes

Reaction equation

HRID 597015 reaction equation
O=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][C:15]#[N:16])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH2:4][CH:3]1[CH2:17][CH3:18].[N-:19]=[N+:20]=[N-:21].[Na+].[Cl-].[NH4+].Cl.CN(C)C=[O:29]>>[O:29]=[C:14]([O:13][C:7]1[CH:6]=[C:5]2[C:10](=[C:9]([Cl:11])[C:8]=1[Cl:12])[CH2:2][CH:3]([CH2:17][CH3:18])[CH2:4]2)[C:15]1[NH:21][N:20]=[N:19][N:16]=1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 25517Ammonium ChlorideHCID 33557Sodium AzideHCID 12395624(1-Oxo-2-ethyl-6,7-dichloro-5-indanyloxy)acetonitrile

Product 1

HCID 178435402HCID 178435402, compound

Procedure

A mixture of (1-oxo-2-ethyl-6,7-dichloro-5-indanyloxy)acetonitrile (7.5 g., 0.0265 mole), sodium azide (2.02 g., 0.031 mole) and ammonium chloride (1.68 g., 0.0031 mole) in dimethylformamide (40 ml.) is heated on a steam bath for one hours and poured into dilute aqueous hydrochloric acid affording 7.3 g. (85%) of 5-(1-oxo-2-ethyl-6,7-dichloro-5-indanyloxymethyl)tetrazole which melts at 205°-206° C. after recrystallization from nitromethane.

Workup

  1. temperatureis heated on a steam bath for one hours
  2. custom(85%) of 5-(1-oxo-2-ethyl-6,7-dichloro-5-indanyloxymethyl)tetrazole which melts at 205°-206° C. after recrystallization from nitromethane

Sources & evidence

ORD record
ord-cea9b5a174af4ec98dbc4abf50d61d08
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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