HCID 12395589, compound → HCID 21449490, compound

HRID 597017Notes

Reaction equation

HRID 597017 reaction equation
[CH:1]1([C:6]2([CH3:19])[CH2:14][C:13]3[C:8](=[C:9]([Cl:17])[C:10]([CH3:16])=[C:11]([OH:15])[CH:12]=3)[C:7]2=[O:18])[CH2:5][CH2:4][CH2:3][CH2:2]1.[H-].COCCO[Al+]OCCOC.[Na+].[H-]>O1CCCC1>[CH:1]1([C:6]2([CH3:19])[CH2:14][C:13]3[C:8](=[C:9]([Cl:17])[C:10]([CH3:16])=[C:11]([OH:15])[CH:12]=3)[CH:7]2[OH:18])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 12395589HCID 12395589, compoundHCID 21584525Sodium bis(2-methoxyethoxy)aluminiumhydride

Product 1

HCID 21449490HCID 21449490, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2-Cyclopentyl-2,6-dimethyl-7-chloroindan-1,5-diol is prepared following substantially the same procedure described in Example 4, Step E, using the following substances: 2-cyclopentyl-2,6-dimethyl-5-hydroxy-7-chloro-1-indanone (8.37 g., 0.03 mole); sodium bis-(2-methoxyethoxy)-aluminum hydride (70% in [10 ml.]); and tetrahydrofuran (100 ml.).

Sources & evidence

ORD record
ord-ab4d358bfcd9412f8e279b04a1e3a602
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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