Aluminum isopropoxide → N~2~,N~5~-Bis(1-hydroxyethylidene)ornithine

HRID 597281Notes

Reaction equation

HRID 597281 reaction equation
[OH-].[Mg+2:2].[OH-].[C:4]([NH:7][C@H:8]([C:16]([OH:18])=[O:17])[CH2:9][CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14])(=[O:6])[CH3:5].CC(C)[O-].[Al+3:23].CC(C)[O-].CC(C)[O-]>O.C(O)(C)C>[Mg:2].[Al:23].[C:4]([NH:7][C@H:8]([C:16]([OH:18])=[O:17])[CH2:9][CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14])(=[O:6])[CH3:5]

Participants

7

Reactant 3

HCID 11143Aluminum isopropoxideHCID 65977N~2~,N~5~-Bis(1-hydroxyethylidene)ornithineHCID 73981Magnesium Hydroxide

Product 2

HCID 65977N~2~,N~5~-Bis(1-hydroxyethylidene)ornithineYield 404.7%HCID 10129885Aluminium magnesium alloy powder

Reagents, catalysts & solvents 2

HCID 962WaterSolvent2×HCID 3776IsopropanolSolvent

Conditions

Temperature
60 °C

Procedure

Magnesium hydroxide (11.66 g.; 0.2 mole) suspended in water (20 cc.) is added to N,N'-diacetylornithine (172.8 g.; 0.8 mole) dissolved in distilled water (1,200 cc.) at 60° C. The reaction mixture is heated and stirred at 60° C for 30 minutes. Aluminium isopropoxide (81.6 g.; 0.4 mole) suspended in isopropanol (100 cc.) is added, and the mixture is then stirred and heated at 60° C for 30 minutes. After treatment of the reaction mixture as in Example 1, a mixed aluminium magnesium salt of N,N'-diacetyl-ornithine (175 g.) is obtained in the form of a white powder corresponding to the formula: ##EQU6## Al% = 5.45 (theory: 5.35) and Mg% = 2.36 (theory: 2.42).

Workup

  1. temperatureThe reaction mixture is heated
  2. additionis added
  3. stirringthe mixture is then stirred
  4. temperatureheated at 60° C for 30 minutes

Sources & evidence

ORD record
ord-643c527a22c64811b5b6bf2e4cd50170
Source dataset
uspto-grants-1977_03
Patent number
US04013699

Reaction notes

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