Aluminum isopropoxide → HCID 7019608, compound

HRID 597282Notes

Reaction equation

HRID 597282 reaction equation
[OH-].[Mg+2:2].[OH-].[C:4]([NH:7][C@H:8]([C:17]([OH:19])=[O:18])[CH2:9][CH2:10][CH2:11][CH2:12][NH:13][C:14](=[O:16])[CH3:15])(=[O:6])[CH3:5].CC(C)[O-].[Al+3:24].CC(C)[O-].CC(C)[O-]>O.C(O)(C)C>[Mg:2].[Al:24].[C:4]([NH:7][C@H:8]([C:17]([OH:19])=[O:18])[CH2:9][CH2:10][CH2:11][CH2:12][NH:13][C:14](=[O:16])[CH3:15])(=[O:6])[CH3:5]

Participants

7

Reactant 3

HCID 11143Aluminum isopropoxideHCID 73981Magnesium HydroxideHCID 7019608HCID 7019608, compound

Product 2

HCID 7019608HCID 7019608, compoundYield 436.7%HCID 10129885Aluminium magnesium alloy powder

Reagents, catalysts & solvents 2

HCID 962WaterSolvent2×HCID 3776IsopropanolSolvent

Procedure

Magnesium hydroxide (3.5 g.) in water (6 cc.) is added to a solution, heated to 60° C, of N,N'-diacetyl-L-lysine (55.2 g.) and water (360 cc.), and then the reaction mixture is kept at 60° C for 30 minutes with stirring. A suspension of aluminium isopropoxide (24.5 g.) in isopropanol (30 cc.) is then added with stirring and while keeping the temperature at 60° C. The isopropanol is removed by distillation under reduced pressure (25 mm Hg). The reaction mixture is then filtered in order to remove insoluble material and the filtrate concentrated to dryness under reduced pressure (25 mm Hg) at 50° C. The paste-like residue obtained is triturated three times in acetone and then dried under reduced pressure (25 mm Hg). A solid is thus obtained which is washed by filtration using acetone (3 × 150 cc.). After drying, a mixed aluminium magnesium salt of N,N'-diacetyl-L-lysine (60.35 g.) corresponding to the formula: ##EQU11## is obtained.

Workup

  1. additionis then added
  2. stirringwith stirring
  3. customat 60° C
  4. customThe isopropanol is removed by distillation under reduced pressure (25 mm Hg)
  5. filtrationThe reaction mixture is then filtered in order
  6. customto remove insoluble material
  7. concentrationthe filtrate concentrated to dryness under reduced pressure (25 mm Hg) at 50° C
  8. customThe paste-like residue obtained
  9. customis triturated three times in acetone
  10. customdried under reduced pressure (25 mm Hg)
  11. customA solid is thus obtained which
  12. washis washed by filtration
  13. customAfter drying

Sources & evidence

ORD record
ord-cf26497494d2452a81315864e69e85db
Source dataset
uspto-grants-1977_03
Patent number
US04013699

Reaction notes

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