Hydrochloric Acid → HCID 121410305, compound

HRID 59783Notes

Reaction equation

HRID 59783 reaction equation
[Cl:1][C:2]1[CH:34]=[CH:33][C:5]([CH2:6][CH2:7][N:8]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[C:29]([O:31][CH3:32])=[O:30])[CH:9]2[CH2:14][CH2:13][N:12](C(OC(C)(C)C)=O)[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.Cl>CCOC(C)=O>[ClH:1].[Cl:1][C:2]1[CH:34]=[CH:33][C:5]([CH2:6][CH2:7][N:8]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[C:29]([O:31][CH3:32])=[O:30])[CH:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 121410323tert-Butyl 4-((4-chlorophenethyl)(2-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate

Product 1

HCID 121410305HCID 121410305, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

tert-Butyl 4-((4-chlorophenethyl)(2-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate obtained in Step 1 was subjected to the deprotection reaction as described in Procedure 2 (4 N HCl in AcOEt).

Sources & evidence

ORD record
ord-524981261554462b9a998662bc876d45
Source dataset
uspto-grants-2016_09
Patent number
US09440953B2

Reaction notes

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