Hexyl isocyanate → HCID 67268410, compound

HRID 598201Notes

Reaction equation

HRID 598201 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][C:9](=[O:18])[N:10](C(OC(C)(C)C)=O)[C:3]=12.[N:19]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[C:20]=[O:21]>CN(C)C1C=CN=CC=1.C1(C)C=CC=CC=1>[CH2:22]([NH:19][C:20]([N:8]1[C:4]2=[N:5][CH:6]=[CH:7][C:2]([CH3:1])=[C:3]2[NH:10][C:9]1=[O:18])=[O:21])[CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]

Participants

5

Reactant 2

HCID 75659Hexyl isocyanateHCID 67268948HCID 67268948, compound

Product 1

HCID 67268410HCID 67268410, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 1140TolueneSolvent

Procedure

Analogously to Example 1, tert-butyl 7-methyl-2-oxo-2,3-dihydroimidazo[4,5-b]pyridine-1-carboxylate (300 mg, 1.2 mmol), 1-isocyanatohexane (183.8 mg, 1.44 mmol) and 4-dimethylaminopyridine (14.7 mg, 0.12 mmol) were reacted in toluene. Yield: 8 mg (2%), M+H+: 277.16.

Sources & evidence

ORD record
ord-15b6fea5e0374100bf33be655bbcc309
Source dataset
uspto-grants-2011_03
Patent number
US07897616B2

Reaction notes

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