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2 M MeNH2 in THF (82 mL) was added dropwise to a solution of 5-bromo-1,3-difluoro-2-nitrobenzene (164 mmol) and Cs2CO3 (197 mmol) in THF (1 L). The reaction mixture was stirred at 0° C. for 1 h and then at room temperature for 1 h. The solvent was removed under reduced pressure. The residue was partitioned between EtOAc and H2O. The two phases were separated and the organic layer was dried (Na2SO4) and concentrated to afford the desired product.

1. waitat room temperature for 1 h
2. customThe solvent was removed under reduced pressure
3. customThe residue was partitioned between EtOAc and H2O
4. customThe two phases were separated
5. dry with materialthe organic layer was dried (Na2SO4)
6. concentrationconcentrated