Oxygen → Cyclooctanone

HRID 599721Notes

Reaction equation

HRID 599721 reaction equation
O=O.[CH:3]1([OH:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1>[Pt].O>[C:3]1(=[O:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

5

Reactant 2

HCID 977OxygenHCID 12766Cyclooctanol

Product 1

HCID 10403CyclooctanoneYield 87%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 962WaterSolvent

Procedure

In an ambient pressure oxygen atmosphere, 26.4 mg of cyclooctanol and 34.1 mg of the platinum catalyst obtained in Example 1 were agitated for twelve hours at 60° C. in 2 ml of water. The reaction mixture was subsequently extracted using ethyl acetate, and the organic layer was dried using magnesium sulfate, filtered and concentrated to obtain 22.6 mg (87% yield) of cyclooctanone. The reaction equation and the analytical results of the product are shown below.

Workup

  1. extractionThe reaction mixture was subsequently extracted
  2. customthe organic layer was dried
  3. filtrationfiltered
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-f36aa0aa904140b9bffe31bce7c19e4d
Source dataset
uspto-grants-2011_03
Patent number
US07897817B2

Reaction notes

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