Oxygen → Cyclooctanone

HRID 599722Notes

Reaction equation

HRID 599722 reaction equation
O=O.[CH:3]1([OH:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1>[Pt].O>[C:3]1(=[O:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

5

Reactant 2

HCID 977OxygenHCID 12766Cyclooctanol

Product 1

HCID 10403CyclooctanoneYield 93%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 962WaterSolvent

Procedure

In an ambient pressure oxygen atmosphere, 25 mg of cyclooctanol and 137 mg of the platinum catalyst obtained in Example 1 were agitated for sixty hours at 60° C. in 2 ml of water. The reaction mixture was subsequently extracted using ethyl acetate, and the organic layer was dried using magnesium sulfate, filtered and concentrated to obtain 22.8 mg (93% yield) of cyclooctanone.

Workup

  1. extractionThe reaction mixture was subsequently extracted
  2. customthe organic layer was dried
  3. filtrationfiltered
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-ec3f67895077445987c8528253357f5c
Source dataset
uspto-grants-2011_03
Patent number
US07897817B2

Reaction notes

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