反应详情

There were mixed 20.3 g (0.15 mole) of acetanilide, 73.1 g (0.18 mole) of 4,4′-diiodobiphenyl, 22.1 g (0.16 mole) of anhydrous potassium carbonate, 2.16 g (0.034 mole) of copper powder and 35 ml of n-dodecane, followed by reaction at 190 to 205° C. for 10 hours. The reaction product was extracted with 200 ml of toluene, and the insoluble matter was removed by filtration. Then, the filtrate was concentrated to dryness. The resulting solid matter was purified by column chromatography (carrier: silica gel, eluate: toluene/ethyl acetate=6/1) to obtain 40.2 g (yield: 64.8%) of N-(4′-iodobiphenylyl)acetanilide. The melting point was 135.0 to 136.0° C.

1. customfollowed by reaction at 190 to 205° C. for 10 hours
2. extractionThe reaction product was extracted with 200 ml of toluene
3. customthe insoluble matter was removed by filtration
4. concentrationThen, the filtrate was concentrated to dryness
5. customThe resulting solid matter was purified by column chromatography (carrier: silica gel, eluate: toluene/ethyl acetate=6/1)