Ethyl Bromide → HCID 86600820, compound

HRID 601489Notes

Reaction equation

[CH2:1]([Br:3])[CH3:2].CN(C)CCCNC(C(ON1C(CC)(C)CC([O:24][C:25](=[O:60])[C:26]2[CH:59]=[CH:58][C:29]([C:30]([O:32][CH:33]3[CH2:38][C:37]([CH2:40][CH3:41])([CH3:39])[N:36]([O:42][CH:43]([C:45](=[O:53])[NH:46][CH2:47][CH2:48][CH2:49][N:50]([CH3:52])[CH3:51])[CH3:44])[C:35]([CH2:55][CH3:56])([CH3:54])[CH:34]3C)=[O:31])=[CH:28][CH:27]=2)C(C)C1(CC)C)C)=O.[C:66](#N)C>>[Br-:3].[CH2:55]([C:35]1([CH3:54])[CH:34]([CH3:66])[CH:33]([OH:32])[CH2:38][C:37]([CH2:40][CH3:41])([CH3:39])[N:36]1[O:42][CH:43]([CH3:44])[C:45]([NH:46][CH2:47][CH2:48][CH2:49][N+:50]([CH2:1][CH3:2])([CH3:51])[CH3:52])=[O:53])[CH3:56].[C:30]([O-:32])(=[O:31])[C:29]1[CH:58]=[CH:59][C:26]([C:25]([O-:60])=[O:24])=[CH:27][CH:28]=1

Participants

Reactant 3

HCID 6332Ethyl Bromide

HCID 6342Acetonitrile

HCID 67290352HCID 67290352, compound

Product 1

HCID 86600820HCID 86600820, compound

Procedure

Ethylbromide (7.5 ml) is added to a solution of terephthalic acid bis-{1-[1-(3-dimethylamino-propylcarbamoyl)ethoxy]-2,6-diethyl-2,3,6-trimethyl-piperidine-4-yl} ester (11.0 g, 0.0125 mol) in acetonitrile (20 ml). The mixture is stirred at room temperature for 17 h and is then evaporated to afford 14.1 g of the title compound as a colorless amorphous solid.

Workup

customis then evaporated

Sources & evidence

ORD record: ord-38d88f74491841e0bb3bd88eda8263a6
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07902368B2

Reaction notes

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