Methyl iodide → HCID 23158207, compound

HRID 601652Notes

Reaction equation

HRID 601652 reaction equation
[OH-].[Na+].[Br:3][C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[CH:8]([O:14][C:15](C)=O)[CH2:7]2.[CH3:18]I>CN(C)C=O>[Br:3][C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[C:8]([CH3:18])([O:14][CH3:15])[CH2:7]2

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 14798Sodium HydroxideHCID 23158346HCID 23158346, compound

Product 1

HCID 23158207HCID 23158207, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

640 mg of 60% of sodium hydroxide was added at room temperature to 20 ml solution of dimethylformamide with 850 mg of 5-bromo-2-methylcarbonyloxy-1-indanone obtained in the above 1). After stirring for 10 min at room temperature, 3.5 ml of methyl iodide was added and the mixture was stirred for 1 hour at room temperature. Then, 2 ml of dimethylformamide containing 5% water was added and further stirred for 1 hour at room temperature.

Workup

  1. customobtained in the above 1)
  2. stirringthe mixture was stirred for 1 hour at room temperature
  3. stirringfurther stirred for 1 hour at room temperature

Sources & evidence

ORD record
ord-d40d51d529ac465dadaaee44767af07c
Source dataset
uspto-grants-2011_03
Patent number
US07902369B2

Reaction notes

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