反应详情

tert-Butyl (4-formylphenoxy)acetate (5.0 g, 21.2 mmol) was dissolved in dry toluene (100 mL) and p-toluidine (2.27 g, 21.2 mmol) was added. The mixture was refluxed in a Dean-Stark apparatus for 18 hours, cooled and concentrated under reduced pressure. Heptane was added and the mixture was concentrated under reduced pressure. This afforded the title compound.

1. temperatureThe mixture was refluxed in a Dean-Stark apparatus for 18 hours
2. temperaturecooled
3. concentrationconcentrated under reduced pressure
4. additionHeptane was added
5. concentrationthe mixture was concentrated under reduced pressure