Anisole → 4-Bromo-1-chloro-2-(4-methoxybenzyl)benzene

HRID 604728Notes

Reaction equation

HRID 604728 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH:10]=1)[C:7](O)=O.[C:12]1([O:18][CH3:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH2:7][C:15]2[CH:16]=[CH:17][C:12]([O:18][CH3:19])=[CH:13][CH:14]=2)[CH:10]=1

Participants

3

Reactant 2

HCID 7519AnisoleHCID 331275-Bromo-2-chlorobenzoic acid

Product 1

HCID 223285944-Bromo-1-chloro-2-(4-methoxybenzyl)benzene

Procedure

Synthesis was performed by a similar method as in Preparation Example 14 using 5-bromo-2-chlorobenzoic acid and anisole.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-8880b032085c4f70b5f0b694ff469b41
Source dataset
uspto-grants-2011_03
Patent number
US07910619B2

Reaction notes

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