反应详情

温度

80 °C

1.99 g of 2-bromo-1-phenylethanone, 1.73 g of 2-amino-5-bromopyridine and 1 g of sodium hydrogen carbonate in a mixture of 20 ml of ethanol and 5 ml of water are placed in a round-bottomed flask. The mixture is heated at 80° C. for 4 h and left to cool and 40 ml of water are added. The mixture is stirred for 15 min and the precipitate is then recovered by filtration; it is washed with water and then with diisopropyl ether and dried in a desiccator. 1.8 g of compound are obtained. Mp=192-194° C.

1. customare placed in a round-bottomed flask
2. waitleft
3. temperatureto cool
4. filtrationthe precipitate is then recovered by filtration
5. washit is washed with water
6. dry with materialwith diisopropyl ether and dried in a desiccator